Description
Draxin vial of 100 ml for injections is an antibacterial drug in the form of a solution for injections, containing as an active substance 100 mg/ml of tulathromycin and auxiliary substances: monothioglycerol and water.
Indications
They are prescribed to cattle and pigs for the treatment of bacterial infections of the respiratory organs caused by Actinobacillus pleuropneumoniae, Pasteurella multocida and Mycoplasma hyopneumoniae, Mannheimia (Pasteurella) haemolytica, Haemophilus somnus, Mycoplasma bovis, sensitive to tulathromycin.
Doses and method of application of draxin.
Draxin is administered to cattle subcutaneously once in a dose of 1 ml per 40 kg of animal weight (2.5 mg of tulathromycin per 1 kg of animal weight). When treating
cattle, the weight of which exceeds 300 kg, the dose is divided in such a way that the volume injected at one point does not exceed 7.5 ml.
Draxin is administered to pigs once intramuscularly in the neck area at a dose of 1 ml per 40 kg of animal weight (2.5 mg of tulathromycin per 1 kg of animal weight). When treating pigs whose weight exceeds 80 kg, the dose is divided in such a way that no more than 2 ml is injected into one point.
Pharmacological properties
Tulathromycin is a semi-synthetic antibiotic of the macrolide group. Macrolides are bacteriostatic antibiotics that inhibit protein biosynthesis due to selective binding to bacterial ribosomal RNA. Tulathromycin has in vitro activity against Mannheimia (Pasteurella) haemolytica, Pasteurella multocida, Haemophilus somnus and Mycoplasma bovis, as well as Actinobacillus pleuropneumoniae, Pasteurella multocida and Mycoplasma hyopneumoniae — bacteria that cause respiratory tract diseases in cattle and pigs.
Tulathromycin is quickly resorbed and slowly excreted from the body. The maximum concentration of the drug in the blood is registered after 30 minutes after administration. The drug is excreted by the kidneys.
According to the degree of impact on the body, Draxin belongs to moderately dangerous substances (hazard class 3 according to GOST 12.1.007).
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Contraindications
Individual increased sensitivity of animals to macrolide antibiotics. With individual sensitivity of animals, the development of allergic reactions is possible. In this case, adrenaline and (or) antihistamine drugs are prescribed.
Draxin should not be mixed in the same syringe with other medicinal products. Draxin is not recommended to be prescribed simultaneously with other macrolides or lincosamides.
Personal instructions
Slaughter of cattle for meat is allowed no earlier than 30 days later, and meat at the place of administration of the drug can be used for food purposes no earlier than 55 days after the last application of the drug. If animals are slaughtered earlier than 64 days after the last use of the drug, the liver and kidneys are disposed of. After 64 days, animal livers and kidneys can be used for food without restrictions.
Slaughter of pigs for meat is allowed no earlier than 30 days later, and meat in the place of administration of the drug can be used no earlier than 68 days after the last application of the drug. If animals are slaughtered earlier than 50 days after the last use of the drug, the liver and kidneys are disposed of. After 50 days, animal livers and kidneys can be used for food without restrictions. The meat of animals forcibly killed before the expiration of the specified period can be used for
feeding fur animals or for the production of meat and bone meal.
It is forbidden to use the drug for cows from which milk is obtained for food purposes. Do not use in calving cows or heifers from which it is planned to receive milk for food purposes within 2 months before the expected calving date.
Storage conditions
Store the drug with caution (list B) in a dry place protected from direct sunlight and out of the reach of children, at a temperature of 5 to 25 C. The shelf life of the drug under storage conditions is 3 years from the date of manufacture.
Manufacturer
Zoetis (formerly Pfizer).